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Notably, discontinuation is associated with weight regain and partial or complete reversal of improvements in cardiometabolic risk factors, including inflammatory markers, blood pressure, lipid profile, and blood glucose levels
We had reasonable follow-up for all doses of semaglutide up to 7 months
Several proteins that are affected by Mendelian diseases are targets of existing antihypertensive drugs and other such proteins may be good candidates for future drug development
doi:10.1056/NEJMoa2502082 Verma S, Bttcher M, Brown P, et al
doi: 10.1158/1055-9965.EPI-05-0368