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Both excitatory and inhibitory synaptic genes show decreased expression with age and are positively correlated with BDNF and NTRK2 expression and negatively correlated with dominant-negative truncated NTRK2 level

MCC950, a selective NLRP3 inflammasome inhibitor, successfully suppressed TGF-1 + IL-1-induced NLRP3 inflammasome activation, as indicated by the downregulation of caspase-1 p20 (Fig

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