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However, inhibition of DPP-4 also potentiates the stem cell chemokine, stromal cell-derived factor-1 (SDF-1), which can promote inflammation, proliferative responses and neovascularization

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Clinical data shows average 20-25% body weight reduction, with additional benefits for obstructive sleep apnea in patients with obesity

Three means present and significantly disrupting the day

Have a BMI of 27 or higher (overweight) and have at least one weight-related health condition like high blood pressure, type 2 diabetes, high cholesterol, or sleep apnea