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Reviewers typically look for an HbA1c at or above 7.0 percent for type 2 diabetes coverage, a BMI of 27 or higher with a comorbidity or 30 or higher standalone, a documented trial of metformin or another agent, and cardiovascular history such as coronary artery disease, stroke, or heart failure

People with these genetic changes might need different doses to get the best results

A larger trial-emulation study (SURPASS CVOT NCT06779929) found both medicines offered broadly comparable heart protection in high-risk adults with type 2 diabetes

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But it wasnt perfect