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This dual agonist approach has shown amplified effects in both blood glucose reduction and weight loss when compared to single agonist GLP-1 drugs like Ozempic

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More recently in AWARD-10, the addition of dulaglutide to an SGLT2i also resulted in weight loss, reduced HbA1c, and lower systolic blood pressure [94]

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Studies have demonstrated that improved sleep quality can help restore GM balance and mitigate inflammatory responses, which is beneficial for managing ACM (205, 206)