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Evaluation of T cell responses will also be needed to draw conclusions regarding mechanisms if immunopathology is observed

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J Physiol 552:335344 Tsuchida K, Aoyagi Y, Odani S, Mita T, Isemura M (1995) Isolation of a novel collagen-binding protein from the mushroom, Hypsizigus marmoreus , which inhibits the Lewis lung carcinoma cell adhesion to type IV collagen

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calcium may also enter and damage the mitochondria and disrupt ionic homeostasis, leading to more proteolysis and swelling, impaired axonal transport, and disconnection