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We were also relieved to find out that this association persisted when we accounted for past history of pancreatitis, which is an important risk factor for pancreatic cancer. This finding was particularly important, Dankner said, because physicians often avoid prescribing GLP-1RAs to people with a history of pancreatitis

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Overview of main clinical studies for MASLD/MASH with GLP-1 receptor agonists and dual or triple agonists targeting glucagon/GIP/GLP-1 receptors Liraglutide Liraglutide, a once-daily GLP-1 receptor agonist with authorized indications for type 2 diabetes and obesity, was evaluated in the LEAN trial (NCT01237119), a phase 2 randomized controlled study enrolling 52 adults with biopsy-proven MASH [22]

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c , The indicated plasmids were introduced into H1299 cells

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