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Intraperitoneal administration of high doses of polyethylene glycol (PEG) causes hepatic subcapsular necrosis and low-grade peritonitis with a rise in hepatic biomarkers

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This sustained antioxidant nanozyme not only scavenges ROS in the microenvironment but also resists oxidative stress-mediated ferroptosis and hyperinflammation by inhibiting the expression of the critical factor IL6, highlighting its promise for the clinical therapy of IDD

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