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ClinicalTrials.gov: NCT07567001 (HF-POLARIS) | Mechanism: GLP-1 / amylin dual agonist TRIAL SPOTLIGHT Educational spotlight selected by editors Semaglutide Without the Needle: A Dissolving Microarray Patch Enters the Clinic Terrestrial Bio (formerly Vaxess Technologies) dosed the first patients on July 1, 2026, in a Phase 1 trial (NCT07673900) evaluating VX-201, a needle-free microarray patch branded as Tacterra that delivers the established GLP-1 receptor agonist semaglutide
Bile acids (BAs) Bile Acids (BAs) are another important actor in the modulation of the intestinal permeability and, thus, indirectly of low-grade systemic inflammation, both with a direct modulation of the intestinal barrier, and influencing the gut microbiota composition
Comparative topical-cream study including a copper-binding peptide preparation
No changes in spleen weights, body weights, or muscle weights were observed between groups (Fig
Nausea, diarrhea, vomiting, constipation and stomach pain are most common
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