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In Perseus [29], the table with protein LFQ intensities was as well filtered for contaminants, after which the matrix was further filtered to contain at least three valid values in at least one of the groups

doi: 10.3389/fendo.2014.00056 Received 20 March 2014 Accepted 07 April 2014 Published 22 April 2014 Volume 5 - 2014 Edited by Rosaria Meccariello, University of Naples Parthenope, Italy Reviewed by Rosanna Chianese, Second University of Naples, Italy

NNMT is a known drain on NAD+, and 5-Amino-1MQ appears to inhibit this process by helping maintain more usable NAD+ within cells

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Haem-iron acquisition is coordinated by the ferric uptake regulator fur