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However, after we added a bacterial-type selenocysteine insertion sequence element to the open reading frame we successfully expressed TGR, using the strategy previously employed for production of mammalian TrxR [14,15]

Moreover, tirzepatide has demonstrated anti-inflammatory effects, which are crucial in reducing liver inflammation and preventing disease progression

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In the SURMOUNT-1 trial, participants taking tirzepatide at the 15 mg dose lost an average of 20.9% of their body weight over 72 weeks