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Additionally, metformin can improve endometrial receptivity by increasing the expression of GLUT4 in the endometrium, regulating the expression of hormone receptors related to endometrial decidualization, and modulating autophagy and nucleic acid/protein transcription processes, which in turn improves the reproductive outcomes of PCOS

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Ethics declarations Ethics approval and consent to participate The study followed the principles set forth in the Declaration of Helsinki for medical research involving human subjects

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Dual roles of astrocyte-derived factors in regulation of blood-brain barrier function after brain damage

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