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Background Ketogenic dietary therapies (KDTs) have been widely used to treat epilepsy since the 1920s1930's (1), but their use significantly decreased with the discovery of new anti-seizure medications (ASMs)

Very-low-calorie ketogenic diet as a safe and valuable tool for long-term glycemic management in patients with obesity and type 2 diabetes

Therefore, they come in supplements

However, many researchers are concerned about potential ocular adverse effects with continued use of these medications, most notoriously the controversy about a potential increased risk of ischemic optic neuropathy that has generated several research papersoften contradictorysince last summer

The anticancer effect of celecoxib is COX-2-independent in HT-29 and PC-3 cells and in HT-29 cells primarily via down-regulating LTB 4 production (Gao et al., 2010)

Dosing - A Significant Unknown In published research showing effects, oral berberine doses typically ranged from 900-1500mg daily , often divided into multiple doses taken with meals