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discovered that in prostate cancer (PCa), vitamin C (VC) can induce oxidative stress and apoptosis by inhibiting GS

This suggests that cells have alternate ways to supplement their glutamine supply, Dr

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Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM

NORMAN SWAN: We asked Dr Shah about research suggesting a role for NAD plus in cancer, creatine and the behaviour of tumours and how vitamin C in high doses intravenously, turns from an anti-oxidant into a pro-oxidant

NRTIs have been shown to inhibit the mitochondrial specific DNA polymerase- causing a decrease in mtDNA amount and quality