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Among them, GPX4 is a membrane-associated phospholipid hydroperoxidase, and it is also the only enzyme in the GPX family that directly reduces and destroys lipid hydroperoxides, which can reduce complex lipid compounds in addition to reducing H 2 O 2 and small molecule hydroperoxides

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For example, ongoing research has explored the use of single-cell transcriptomics to establish immune system baselines in ME/CFS patients to compare ME/CFS patients and to detect deviations following cardiopulmonary exercise testing (Vu et al., 2024)