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The filtrate was diluted 200 or 1,000 times with 0.1% formic acid in Milli-Q (MQ) water and then applied to an LCMS-8040 system (Shimadzu Co.) to quantify felinine and its related compounds, 3-methylbutanol glutathione (MBG), 3-methylbutanol cysteinyl-glycine (MBCG), and N -acetylfelinine, based on a previous report (Futsuta et al., 2018)

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Nov 1: Mercks blockbuster Keytruda racked up another FDA approval Wednesday, as the company announced that the anti-PD-1 therapy is now authorizedin combination with gemcitabine and cisplatinto treat patients with locally advanced unresectable or metastatic biliary tract cancer (BTC)

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