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(Table 2)

The hepatotoxic effects of APAP are localized to the centrilobular region, where cytochrome P450 2E1 is highly expressed

Without it, almost nothing happens

Additional research has explored Epithalon's effects on melatonin production, antioxidant enzyme levels, and circadian regulation in aging animal models

However, antioxidants can interfere with chemotherapy, so their use is controversial