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If not treated, CHF and death may occur

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Cushings Syndrome and Cushing Disease

doi: 10.3389/fendo.2024.1528457 Received 14 November 2024 Accepted 30 December 2024 Published 21 January 2025 Volume 15 - 2024 Edited by Claire Joanne Stocker, Aston University, United Kingdom Reviewed by Wael Sidrak, Abou Seifein Diabetes & Endocrine Center, Egypt Frederic Illouz, CHU Angers, France Christine Trapp, Connecticut Childrens Medical Center, United States Updates Copyright 2025 Koceva, Mleku Kozamernik, Jane, Herman, Ferjan and Jensterle

These include prolonged immobility, recent surgery, active cancer, pregnancy, use of combined hormonal contraceptives or hormone replacement therapy, previous history of blood clots, inherited thrombophilias, obesity, smoking, and increasing age

Combined with exercise therapy, both proved more effective than just exercise alone [53]