Low blood sugar (especially with diabetes medicines): Headache, confusion, shakiness, sweating, fast heartbeat
Acacia ferments slowly, so you get the microbiome benefit without the bloat
Finally, some sensitive individuals may experience mild gastrointestinal upset, such as diarrhea or cramping, when first introducing 5-HTP, simply because the gut is rapidly waking up from a paralyzed state
Glucagon-like peptide-1 receptor (GLP-1) agonists, widely used to treat obesity and diabetes, may also improve key outcomes for patients with Crohns disease, according to a large real-world study presented during the 2026 Crohns & Colitis Congress, a partnership of AGA and the Crohn's & Colitis Foundation, taking place in Las Vegas
However, if you have a history of medullary thyroid cancer, multiple endocrine neoplasia syndrome type 2, or severe gastrointestinal problems, discuss alternate options with your provider
An eight-week, double-blind study found that 400 mg of L-theanine per day was safe and effective while also possessing neuroprotective, mood-enhancing and relaxation properties