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The TRIUMPH-4 trial studied 445 adults with obesity or overweight and knee osteoarthritis over 68 weeks

Microdosing was not part of those studies

As a result of their research, the group in Copenhagen independently came to essentially the same conclusion as the Boston team that the biological activity of GLP-1 lay in a truncated form of the peptide which they identified as starting at residue 78 on the peptides sequence (Holst 2019

If you notice these differences, there are ways to support your confidence and comfort during treatment: Your treatment plan can also be adjusted to support more gradual progress if needed

What to expect during the titration period: Initial low dose: Patients typically start at a lower weekly dose