Looking to the next generation of obesity treatments, combinations of GLP-1 with other entero-pancreatic hormones with complementary actions and/or synergistic potential (such as glucose-dependent insulinotropic polypeptide (GIP), glucagon, and amylin) are under investigation to enhance the WL and cardiometabolic benefits of GLP-1 RA
However, with the progression of research, it has become evident that GLP-1R is broadly distributed across various organs and tissues, including but not limited to the brain, heart, kidneys, intestines, eyes, and the vascular system (Song et al., 2017)
Rather than broadly applying this therapy if it is approved, we suggest careful patient selection and monitoring by clinicians pending further studies
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Carl Zeiss, Oberkochen, Germany)
Physical Activity Exercise becomes especially important after stopping GLP-1 medication because it helps: Preserve muscle mass Support metabolism Improve insulin sensitivity Maintain energy balance Strength training, walking, and regular movement can all play a major role in maintaining healthy weight loss results over time
