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Promotes breakdown of liver fat (hepatic steatosis): GCGR activity boosts fatty acid oxidation in the liver, explaining marked reductions in hepatic fat seen in trials 1,2

The increase was modest and did not produce clinical events in the trial population, but researchers with pre-existing cardiovascular conditions should factor this into their risk assessment

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Pain that intensifies instead of fading

Regardless of the cause, particulate matter means the vial should not be used