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Furthermore, neuroinflammation can induce aggravating factors such as bloodbrain barrier disruption, altered neurotransmitter metabolism, oxidative stress, and neurodegeneration [38]

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Oxidative stress: the role of estrogen and progesterone

Together, these results suggest that the activation of OB GLP-1R leads to an increase in insulin secretion through inhibition of SNS activity

Other concerning risks include intestinal blockages, pancreatitis, and rare but severe gallbladder complications such as cholecystitis (inflammation)