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In their efforts to develop a series of StAMPs with limited nonspecific membrane toxicity based on Mag2, Mourtada and co-workers [87] discovered that when the hydrocarbon staple was positioned within one of the high hydrophobicity patches on the AMPs helical, the hemolytic activity remained similar to the native AMP

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Our lab has tested these extensively, and our findings are quite clear

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The activation of the Wnt signaling pathway was also shown to accelerate the proliferation of airway smooth muscle cells, which are involved in airway remodeling