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Based on domain architecture comparison with HNF4 58,59 , we engineered an NHR-49 truncation (295422) to disrupt ligand binding by removing a majority of the ligand binding domain, while retaining its analogous N-terminal, DNA-binding, hinge, and C-terminal domains (Fig

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Thus the most widely adopted methodology for quantification of GSH and GSSG is determination of total GSH concentration, followed by alkylation to remove GSH and then reduction of GSSG and its quantification

Kim YC, Won HK, Lee JW, Sohn KH, Kim MH, Kim TB, Chang YS, Lee BJ, Cho SH, Bachert C, Song WJ