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The SUSTAIN-6 CVOT [67], performed in 3,297 patients with T2DM and ASCVD/CKD, has shown that compared to placebo, semaglutide was associated with increased retinopathy complications (3.0% versus 1.8%

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It works by mimicking the incretin hormones, enhancing insulin secretion, and reducing glucagon levels, which aids in controlling blood sugar

By reducing stomach acid, it helps prevent acid from irritating the lining of the esophagus and stomach