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While niacin supplementation can improve muscle mass and positively impact lipid profiles 15 in mitochondrial disease patients and healthy population, it has been also associated with hyperglycemia 28

Dosage begins at 3 mg daily for 30 days, then increases to 7 mg daily for at least 30 days, with potential escalation to 14 mg if additional glycemic control is needed

The research was funded by the Norwegian Research Council (FRIMEDBIO276010)

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Neuroinflammation 20:234

Medicare-eligible patients may qualify for FDA-approved GLP-1 medications for as little as a $50 copay through the Medicare GLP-1 Bridge Program, while compounded medications are available for $140 per 4-week supply