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Patch testing with tocopherol and tocopherol acetate: the North American Contact Dermatitis Group experience, 2001 to 2016

The SELECT trial (N=17,604) demonstrated that semaglutide 2.4 mg reduced the composite endpoint of cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke by 20% in adults with established cardiovascular disease and overweight or obesity, independent of diabetes status (HR 0.80

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Images by ESB Professional, Eviart/Shutterstock Immunology & inflammation R&D trends and breakthrough innovations

SAR425899 (Sanofi) is another example of a GLP-1/glucagon co-agonist which has been tested in Phase 1 trials

Safety and unknowns GLP-1 drugs are strong medicines: Common side effects: nausea, vomiting, diarrhoea, constipation Possible nutrition issues if eating becomes very limited Limited data around implantation and very early pregnancy