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This paradoxical effect underscores the importance of careful dosing in therapeutic applications

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The H 2 S-related RSS per-sulphides and poly-sulphides can be generated by the same enzymatic systems that are involved in H 2 S metabolism, and play a possibly as-yet-underestimated role in signalling in human health and disease, 102,103,104 which is also briefly discussed below

GHK-Cu is a tripeptide (glycine-histidine-lysine) complexed with a single copper(II) ion