Gastrointestinal distressnausea, vomiting, constipationis most frequent, especially early on
Other reported effects Beyond GI symptoms, clinical trials noted several other effects worth monitoring: Increased heart rate: A small, dose-dependent increase in resting heart rate was observed, consistent with what occurs with other GLP-1 agonists
GLP-1 Receptor Activation The GLP-1 component is the most familiar piece
This can help counteract the effects of metabolic adaptation that cause plateaus during weight loss
However, clinical studies have not demonstrated clinically significant alterations in the bioavailability or therapeutic effect of these agents when co-administered with semaglutide
licensed medical provider will determine whether you are eligible for treatment