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Inflammatory markers such as TNF- and IL-6 are also under active investigation, particularly in studies evaluating anti-cytokine therapies (e.g., infliximab, tocilizumab) [342]

While highly effective at lowering recurrence rates, tamoxifen can trigger metabolic changes that promote weight gain, increase appetite, and slow energy expenditure

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Other antacids containing aluminium hydroxide or magnesium carbonate can provide rapid, short-term symptom relief for occasional heartburn

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