Andrologia, 49, e12712
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At the same time, rosmarinic acid promotes the upregulation of TH and brain-derived neurotrophic factor (BDNF) genes to alleviate the cytotoxicity of H 2 O 2 -induced N2A cells (Ghaffari et al., 2014)
The OCTN subclade, comprised of OCTN1 (SLC22A4) and OCTN2, are a distinct subgroup of OCTs that primarily catalyse the uptake of the zwitterionic metabolites ergothioneine 13 and carnitine respectively, but are also capable of transporting cations such as tetraethylammonium (TEA) 14,15 indicating a potential dual transport function 15,16
Emerging research suggests that GLP-1RAs may also be beneficial in treating conditions like obstructive sleep apnea (Malhotra et al., 2024), osteoarthritis (Bliddal et al., 2024), metabolic dysfunction-associated steatotic liver disease (MASLD) and steatohepatitis with liver fibrosis (MASH) (Loomba et al., 2024), polycystic ovary syndrome (PCOS) (Szczesnowicz et al., 2023), Alzheimers disease (Liang et al., 2024), Parkinsons disease (Kalinderi et al., 2024), and addiction (Klausen et al., 2022)
doi: 10.1002/art.39785 114 BalakrishnanBLuckeyDBodhkeRChenJMariettaEJeraldoPet al
