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As such, excessive stress, diet, oxidative stress levels, and the like can all interfere with how much glutathione someone is producing and, therefore, how well their antioxidant defenses are working

Around age 45, our glutathione levels start to slip

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Additionally, MOTS-c helps cells adapt to metabolic stress by upregulating protective genes and downregulating inflammatory responses

It also noted the occurrence of side effects, including nausea, flushing, and spontaneous erections in male subjects, which, while unintended, led to further research into its use for sexual dysfunction