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Multivariable analysis (partial least squares-discriminant analysis) revealed that urinary metabolite profiles differed depending on the presence or absence of TLS in the kidney, and GSH was one of the metabolites that exhibited the most significant alterations (Figure 6, F and G)

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1991;91:14S22S

This underscores the critical role of SLC25A39-mediated mitochondrial GSH import in maintaining cellular redox balance and overall mitochondrial function

Kim KY, Kim DS, Lee SK, Lee IK, Kang JH, Chang YS, Jacobs DR, Steffes M, Lee DH