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Lloyd, A

Dose changes or stopping treatment without medical advice may affect its efficacy and side effects

[PubMed: 24222016] 477

The vial size should not be read as an implicit dosing signal

First, its interplay with lipid metabolism: surplus pyruvate generated through glycolysis is converted to acetyl-CoA, which can enter lipid biosynthetic pathways and promote the synthesis of fatty acids, particularly PUFAs