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A patient with GLP1R variants associated with lower receptor sensitivity may benefit from earlier dose escalation, while one with higher predicted sensitivity might achieve excellent results at 0.25mg

Dehydroepiandrosterone (DHEA) may inhibit mitophagy via suppression of AMPK/SIRT1 pathway (Ma et al., 2024)

Second, with the updating of evidence-based medicine, the extension of the clinical application period of drugs, the price changes brought about by the tendering and purchasing of drugs, the adjustment of the national essential drug list, the adjustment of the national health insurance list, and the development of drug manufacturers, the changes will further affect our evaluation indexes and results

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Analysis of post-interventional body weights across 18 studies (904 participants) demonstrated significant reductions with phentermine/topiramate (WMD: 11.99