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Elevated homocysteine is a known endothelial toxin that directly contributes to this vascular damage

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Aschner, M., Eberle, N

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doi: 10.3389/fpsyg.2021.666347 Received 10 February 2021 Accepted 02 December 2021 Published 05 January 2022 Volume 12 - 2021 Edited by Gianluca Castelnuovo, Catholic University of the Sacred Heart, Italy Reviewed by Ningxi Yang, Harbin Engineering University, China

Fecal microbiota transplantation and replenishment of short-chain fatty acids protect against chronic cerebral hypoperfusion-induced colonic dysfunction by regulating gut microbiota, differentiation of Th17 cells, and mitochondrial energy metabolism