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Serotonin (5-hydroxytryptamine or 5-HT) metabolites Several studies have described neuronal loss, and presence of Lewy body in serotonergic raphe nuclei in PD patients (Benito-Len et al., 1993b,c, 1997) reported a 1520% reduction of CSF 5-HT, tryptophan (precursor of 5-HT), kynurenine and 3-hydroxykynurenine (metabolites of tryptophan) levels in PD patients

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Nutrients 15 , 479 (2023)