The recommended dosages are based on the data from clinical trials for that specific use. For both types, higher doses may lead to negative side effects Increasing the dosage for both types of medications can come with negative side effects (nausea, vomiting, constipation, fatigue, loss of appetite and more)
Because microbiomes differ, the amount of TMAO produced after carnitine varies by person
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Bardo, Opposite regulation of conditioned place preference and intravenous drug self-administration in rodent models: motivational and non-motivational examples