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While we usually think about low B12 causing anemia, a few case reports describe new or worsened polycythemia - an elevated red cell mass - after B12 administration

Deng G, Ren J, Li R, Li M, Jin X, Li J, et al

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However, further research is warranted to develop comprehensive, evidence-based guidelines that fully harness this synergy, maximising therapeutic benefits while minimising associated risks

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