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In some POTS is felt due to a dysfunctional hypothalamus-pituitary-adrenal (HPA) axis that comes with a paradox low renin and low aldosterone in the face of low blood volume (POTS paradox)

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Research from the journal Experimental Gerontology describes a theory where deteriorating melatonin rhythms cause other circadian rhythms to weaken and desynchronize, contributing significantly to the aging process itself and rendering the body more susceptible to age-related diseases

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Each strip is engineered to dissolve quickly when placed against oral mucosa, providing a consistent delivery format for researchers evaluating buccal administration characteristics