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The HSD17B1 and HSD17B3 encoded enzymes are involved in the synthesis of the male and female sex hormones

doi: 10.1021/acsnano.7b07878 175 KandemirAkarasNimekHGrCleritrkMKklerSet al

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Principal component analysis (PCA) confirmed significant metabolic divergence between the pneumonia groups and healthy controls (Figure 1B)

However, most available randomized data derive from subgroup, post hoc, or exploratory analyses rather than trials specifically designed to evaluate dual therapy in HF populations