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3,4 It is estimated that the annual global health care spending on diabetes among people aged 2079 was US$ 966 billion in 2021, and is estimated to reach more than $1054 billion by 2045

Whilst formulations can differ between product lines, ingredients frequently found in this category of supplement include: Caffeine or green tea extract claimed to boost metabolism and increase thermogenesis (heat production in the body) Glucomannan a dietary fibre derived from the konjac plant, said to promote feelings of fullness Green coffee bean extract containing chlorogenic acids, purported to influence glucose metabolism B vitamins included to support normal energy-yielding metabolism Chromium a trace mineral sometimes included for its claimed role in normal macronutrient metabolism Some products may also contain synephrine or yohimbine, stimulant compounds associated with increases in blood pressure and heart rate

Minkler PE, Brass EP, Hiatt WR, Ingalls ST, Hoppel CL

(2014) 307:E7183

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Front Pharmacol 13:917256 Zhu XD, Lei XP, Dong WB (2017) Resveratrol as a potential therapeutic drug for respiratory system diseases