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The objective of this review is to critically assess the current evidence surrounding their mechanisms of action, clinical indications, efficacy, and safety profiles, with particular emphasis on regulatory and translational considerations

hepatic glucose-output models

And guidance on monitoring requirements and follow-up intervals could also lead to reduced variation in care, he added

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In the coming months, the US Food and Drug Administration will assess a slew of monoclonal antibodies mostly, but not exclusively, for cancer indications

Mann says