In summary, different GLP-1RAs improve skeletal muscle atrophy through multiple molecular mechanisms, involving multiple pathways such as insulin resistance regulation, inflammation suppression, and mitochondrial function improvement (see Table 1), providing a theoretical basis for the clinical treatment of sarcopenia with GLP-1RAs
Side effects As Rybelsus and Ozempic both contain the same active ingredient, semaglutide, their side effects are very similar
Some early research and off-label use suggests smaller doses may still produce measurable improvements in inflammation markers, especially in patients dealing with autoimmune conditions, insulin resistance, chronic joint pain, or PCOS
Hence, a well-designed clinical trial should be conducted in the future before these botanical drugs can be recommended for the treatment of UF
Lombard, A.L
The absorption process of flavonoids is complicated and affected by their chemical structure, solubility, membrane permeability, and the metabolism of gut microbiota
