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FDA accessdata.fda.gov (2025) 6

Orally in the treatment of anemia due to insufficient dietary intake of vitamin B12 in strict vegans: pour the contents of the ampoule into a glass of water As an initial treatment: one ampoule per day for 15 days to 1 month

Without carbidopa, so much levodopa would need to be ingested to allow for a small amount to make it into the brain, that the side effects of the levodopa, specifically nausea, would not be tolerated by most people

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But again, if you're a vegan or follow a strict vegetarian diet, it can be hard to get enough B12 in your diet