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This metabolic wiring generates oxidizable PUFA-phospholipid species that can subsequently undergo enzymatic peroxidation (for example, via lipoxygenases) or non-enzymatic oxidation driven by iron-dependent reactive oxygen species, thereby establishing a lipid network that amplifies ferroptotic vulnerability

Thighs and arms, where smaller pockets of fat may affect overall proportions

Proper storage and handling are key to preserving their effectiveness and ensuring patient safety

The goal is to see whether these early benefits can last over a longer period

There are however several popular alternatives that are described in Notes 1 and 2

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