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At the organismal level, NAD + repletion remarkably extended lifespan and delayed accelerated aging, including stem cell dysfunction, in C

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Moreover, HGF gene transfer with viral vectors reduces pain and inflammation in a neuropathic model (Tsuchihara et al., 2008), promotes neurite extension, and increases synaptogenesis in a stroke model (Shimamura et al., 2006)

2001 Oct;25(10):1442-9

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