doi:10.1002/14651858.CD004655.pub2
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Continuous sun exposure, harsh detergents, dust, pollution, and daily outdoor activities cause the skin on hands and feet to become darker and uneven over time
In addition, senescence-associated secreted factors, such as interleukin 6 (IL-6), interleukin 8 (IL-8), also displayed similar expression profiles, particularly in Cys 2 -starved and erastin-treated cells (Fig
Antioxidants & redox signaling 10 , 445473, doi: 10.1089/ars.2007.1716 (2008)