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Oxidative dimerization in metallothionein is a result of intermolecular disulphide bonds between cysteines in the -domain

The relation between lung function and dietary intake of the antioxidant vitamins C and E in the general population was investigated in a cross-sectional survey of a random sample of adults of Nottingham, England (Britton et al., 1995)

doi: 10.1016/j.tips.2023.04.006 123 GeSZhongHMaXZhengYZouYWangFet al

PMID: 31910118

This leads to a situation where white blood cells such as macrophages continue producing cytokines and, while continuing their attack on foreign microbes, release reactive oxygen species (ROS) and other chemicals that harm normal tissue

Smoking and alcohol consumption are two of the most significant glutathione depleters